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Jeffrey W Smith Selected Research

valilactone

9/2008Synthesis of novel beta-lactone inhibitors of fatty acid synthase.

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Jeffrey W Smith Research Topics

Disease

25Neoplasms (Cancer)
01/2017 - 03/2002
6Melanoma (Melanoma, Malignant)
04/2015 - 04/2009
5Breast Neoplasms (Breast Cancer)
03/2015 - 03/2002
4Sepsis (Septicemia)
04/2022 - 06/2017
3Infections
04/2022 - 07/2007
3Colonic Neoplasms (Colon Cancer)
02/2016 - 10/2007
3Obesity
01/2016 - 03/2004
3Carcinogenesis
03/2015 - 01/2007
3Colorectal Neoplasms (Colorectal Cancer)
04/2012 - 10/2007
3Anthrax
07/2008 - 07/2005
3Carcinoma (Carcinomatosis)
07/2008 - 07/2005
2Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
02/2016 - 05/2011
2Hypoxia (Hypoxemia)
05/2012 - 12/2011
2Multiple Sclerosis
10/2009 - 01/2009
2Demyelinating Diseases (Demyelinating Disease)
10/2009 - 01/2009
2Neoplasm Metastasis (Metastasis)
04/2009 - 06/2002
2Influenza in Birds (Avian Flu)
07/2008 - 07/2007
2Dengue (Dengue Fever)
06/2008 - 02/2007
2West Nile Fever
12/2007 - 01/2006
1Bacteremia
04/2022
1Pathologic Processes
01/2021
1Thrombosis (Thrombus)
02/2016
1Hyperlipidemias (Hyperlipidemia)
01/2016
1Atherosclerosis
01/2016
1Hepatocellular Carcinoma (Hepatoma)
01/2015
1Thymoma (Thymic Carcinoma)
01/2015
1Liver Neoplasms (Liver Cancer)
01/2015
1Biliary Liver Cirrhosis (Primary Biliary Cirrhosis)
04/2012
1Adenoma (Adenomas)
02/2012
1Cutis Laxa
01/2012
1Schizophrenia (Dementia Praecox)
01/2012
1Atherosclerotic Plaque (Atheroma)
09/2010
1Inflammation (Inflammations)
10/2009
1Sarcoma (Soft Tissue Sarcoma)
04/2009
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
01/2009

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
04/2022 - 11/2003
9Pharmaceutical PreparationsIBA
04/2012 - 03/2004
7EnzymesIBA
01/2021 - 06/2002
7Fatty Acid Synthases (Fatty Acid Synthase)IBA
01/2017 - 03/2004
6Glutamine (L-Glutamine)FDA Link
04/2015 - 12/2011
6Matrix Metalloproteinases (MMPs)IBA
10/2009 - 03/2002
4ProteomeIBA
04/2022 - 07/2005
4CarbonIBA
04/2015 - 07/2008
4Fatty Acids (Saturated Fatty Acids)IBA
05/2012 - 01/2007
4Orlistat (Xenical)FDA Link
09/2008 - 03/2004
3IntegrinsIBA
02/2016 - 03/2002
3Bile Acids and Salts (Bile Acids)IBA
02/2016 - 10/2007
3Glucose (Dextrose)FDA LinkGeneric
05/2012 - 03/2010
3FurinIBA
10/2009 - 03/2002
3Peptides (Polypeptides)IBA
01/2009 - 01/2006
2Metalloproteases (Metalloproteinases)IBA
04/2022 - 07/2005
2Anti-Bacterial Agents (Antibiotics)IBA
04/2022 - 06/2017
2Peptide Hydrolases (Proteases)FDA Link
01/2021 - 02/2007
2Deoxycholic Acid (Sodium Deoxycholate)IBA
02/2016 - 10/2007
2Carrier Proteins (Binding Protein)IBA
03/2015 - 10/2007
2Ursodeoxycholic Acid (Urso)FDA LinkGeneric
04/2012 - 02/2012
2Lactic Acid (Lactate)FDA LinkGeneric
12/2011 - 03/2010
2Proprotein Convertases (Pro-Opiomelanocortin Converting Enzyme)IBA
10/2009 - 07/2007
2Myelin Basic ProteinIBA
10/2009 - 01/2009
2Hemagglutinins (Hemagglutinin)IBA
07/2008 - 07/2007
2Serine Proteases (Serine Protease)IBA
06/2008 - 02/2007
2Matrix Metalloproteinase 14 (MT1-MMP)IBA
12/2007 - 03/2002
1Blood Coagulation Factors (Coagulation Factor)IBA
04/2022
1CoagulantsIBA
04/2022
1Biomarkers (Surrogate Marker)IBA
04/2022
1Proteasome Endopeptidase Complex (Proteasome)IBA
01/2017
1Palmitic Acid (Hexadecanoic Acid)IBA
01/2017
1RNA (Ribonucleic Acid)IBA
02/2016
1DNA (Deoxyribonucleic Acid)IBA
02/2016
1chondroitin sulfate proteoglycan 4IBA
01/2016
1Apolipoproteins E (ApoE)IBA
01/2016
1LDL Lipoproteins (beta Lipoproteins)IBA
01/2016
1Aspartic Acid (Aspartate)FDA Link
04/2015
1AsparagineIBA
04/2015
1Glutamic Acid (Glutamate)FDA Link
04/2015
1Paclitaxel (Taxol)FDA LinkGeneric
03/2015
1Mechanistic Target of Rapamycin Complex 1IBA
01/2015
1TOR Serine-Threonine KinasesIBA
01/2015
1Eukaryotic Initiation Factor-4EIBA
01/2015
1Oxidoreductases (Dehydrogenase)IBA
05/2012
1isocitric acid (isocitrate)IBA
05/2012
1Citric Acid (Citrate)FDA LinkGeneric
05/2012
1Acetyl Coenzyme A (Acetyl-CoA)IBA
05/2012
1CholesterolIBA
02/2012
1Proline (L-Proline)FDA Link
01/2012
1Tricarboxylic AcidsIBA
12/2011
1CateninsIBA
05/2011
1OligonucleotidesIBA
09/2010
1Membrane Proteins (Integral Membrane Proteins)IBA
03/2010
1Crystallins (Crystallin)IBA
10/2009
1LipidsIBA
10/2009
1matrix metalloproteinase 25IBA
10/2009
1OsteopontinIBA
04/2009
1aspartic acid glycine arginineIBA
04/2009
1Protein Isoforms (Isoforms)IBA
01/2009
1PalmitatesIBA
11/2008
1Caspase 8 (Caspase-8)IBA
11/2008
1ATP Citrate (pro-S)-Lyase (Citrate Synthase, ATP)IBA
11/2008

Therapy/Procedure

5Therapeutics
04/2022 - 07/2007
1Drug Therapy (Chemotherapy)
03/2015